Crest + Oral-B US Thought Leader Site

There is a misconception that all fluorides are the same. This is simply not true. Stannous fluoride is unique among fluoride compounds offering gingival health benefits not found with sodium fluoride or sodium monofluorophosphate. While all three compounds provide anti-caries benefits, stannous fluoride, when effectively stabilized, has demonstrated broader and significantly greater protection than other fluorides against plaque, gingival health and erosive toothwear.

• Sodium fluoride main mechanism is remineralization or anti-caries

• Stannous fluoride

• Treats and protects gingival health

• Protects against erosive toothwear

• Treats dentinal hypersensitivity

• Remineralizes for anti-caries

• Demonstrated up to 4mm subgingivally

• Substantive for 12 hours

Scientific evidence indicates that anti-bacterial activity of stannous fluoride against both gram positive and negative bacteria inhibits bacterial metabolism. Bacterial exposure to stannous reduces bacterial growth, adhesion, reduced EPS production, and the production of acids and other metabolic toxins that contribute to gingivitis.

Stannous also binds to LPS to prevent triggering host-response including the inflammatory cascade and reduction of markers of oxidate stress.

• Stabilized stannous fluoride defends teeth against acid erosion by creating a highly acid resistant and protective layer over the teeth.

• The deposition of stannous ions at the tooth surface helps to protect it against dental erosion.

• Deposition occurs primarily as a result of the attachment of the stannous ion to free phosphate sites on the surface of enamel.

• Relative to other fluorides, the stabilized stannous fluoride technology provides greater protection against enamel erosion.

• Strengthens enamel through remineralization by deposition of fluoride.

• Dental erosion is irreversible and therefore must be prevented.

Stannous fluoride provides a fast acting and durable, long-lasting occlusion of the dentinal tubules.

Stannous fluoride antibacterial dentifrice can help patients maintain health around implants.

• Rebalances the oral microbiome

• Dose dependent response

• Brushed vs. unbrushed areas (effect beyond mechanical)

• Formulation bioavailability matters

• Up to 4mm below the gumline for 12 hours post-brushing

A score of 250 or less is considered “safe for a lifetime of use”. Normal toothbrushing habits with toothpastes that conform to ISO standard will, in a lifetime of use, cause virtually no wear of enamel and clinically insignificant abrasion of dentin. (Addy & Hunter, 2003)

All oxidative tooth whitening results are directly tied to both:

• Concentration - higher concentration enables faster whitening results and diffusion of the peroxide to the stains below the enamel surface and

• Contact Time – increasing the amount of time the peroxide is in contact with the tooth will increase the results.

The serum contains highly active microdroplets of hydrogen peroxide in a water-resistant base, providing whitening while keeping teeth hydrated. Patients can achieve visibly whiter teeth in 2 weeks with 3% hydrogen peroxide.

The sources of natural tooth color include structural features of the teeth including thickness, translucency, dentin color, and in the absence of staining, may be dominated by genetic factors. Digital Image Analysis (DIA) removes subjectivity to assess changes in:

• Yellow to blue (Δb*)

• Lightness - whiteness (ΔL*)

• Luminescence: Red to Green (Δa*)

Tooth-whitening options include surface stain removal and chemical inhibition via abrasive or chelants, as well as in-office oxidative whitening, and take-home, over the counter oxidative whitening.

Sensitivity is a common side effect of tooth-whitening procedures. This sensitivity is transient and not harmful; the smear layers are not etched. The toxicological data show no evidence for risk. Current belief is that the sensitivity is directly related to rate of whitening and is solely related to peroxide. However, in reality the gelling and adhesive agents also contribute to sensitivity through dehydration of the tooth surface.

Light in tooth-whitening does work if correctly applied. The light must be of the right intensity, applied for the correct period of time and should be applied once the peroxide has been in contact with the tooth surface for the recommended period of time. Correctly applied light will not add sensitivity.

Peroxide is the most extensively researched whitening technology and has been evaluated in short term and extended use clinical trials in a variety of patient populations. P&G has over 183 published papers and presentations evaluating whitening products.